Bring Single Use Technology To Microbial Fermentation Ge Healthcare Ge healthcare uk limited amersham place, little chalfont buckinghamshire, hp7 9na uk ge healthcare europe, gmbh munzinger strasse 5 d 79111 freiburg germany ge healthcare bio sciences corp. 800 centennial avenue, p.o. box 1327 piscataway, nj 08855 1327 usa ge healthcare japan corporation sanken bldg., 3 25 1, hyakunincho. The single use xcellerex™ xdr 500 mo fermentor is a 500 l system specifically designed for growth of microbial cultures. the fermentor delivers reliable performance you can trust even under demanding conditions. with a robust design, the system exhibits powerful mass transfer, efficient temperature control, and excellent gas dispersion.
Pioneering Single Use Technology For Microbial Fermentation Ge In recent years, both ge healthcare (xcellerex) and thermo fisher scientific have launched single use fermentors that mimic the principles of stainless steel systems and reportedly match them in performance as well (5, 6). here, we report on our evaluation of a ge xdr 50 sus fermentor and a thermo scientific hyperforma s.u.f. 30 sus fermentor. Other than a limitation to low overlay head pressure not exceeding 1 psig, sufs do not exhibit any inherent design or material limitations for oxygen transfer from the sparged gas to the liquid culture. heat transfer rates are lowered by the single use liner, requiring augmented designs and operational methods to compensate. 2. application note: performance of single‑use xcellerex xdr‑500 mo and xdr‑50 mo stirred‑tank fermentor systems. ge healthcare, 29253229, edition aa (2016). ordering information fig 3. single‑use fermentation medium preparation equipment and supplies. feed solution base medium small volume additives chemicals for consumption. Fermentation in single use versus stainless steel equipment in this white paper, we compare production capacity and process economy between stainless steel and single use equipment in microbial processes. economy simulations were based on an e. coli dab process. production scenarios in both single and multi product facilities were considered.
Single Use Technology For Microbial Fermentation Processes Ge 2. application note: performance of single‑use xcellerex xdr‑500 mo and xdr‑50 mo stirred‑tank fermentor systems. ge healthcare, 29253229, edition aa (2016). ordering information fig 3. single‑use fermentation medium preparation equipment and supplies. feed solution base medium small volume additives chemicals for consumption. Fermentation in single use versus stainless steel equipment in this white paper, we compare production capacity and process economy between stainless steel and single use equipment in microbial processes. economy simulations were based on an e. coli dab process. production scenarios in both single and multi product facilities were considered. Adoption of single use technology in fermentation processes has been hampered by the lack of systems capable of accommodating the demands of microbial cultures in terms of, for example, sufficient oxygen transfer capacity and temperature control. the single use xcellerex™ xdr 50 mo fermentor is designed to overcome these limitations. The same gains can be achieved by using single use systems for fermentation and the hurdles to adoption have been lowered by the experience in cell culture. this post is sponsored by cytiva (formerly ge). ken clapp explores the implementation of single use systems for microbial fermentation including which processes make good candidates for.
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